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When you inhale a lit cigarette, the nicotine is broken down into more than 15 different substances, including cotinine, anabasine, and nornicotine

While the risk to users is a significant consideration for whether or not a product receives authorization through the PMTA pathway, such considerations must be weighed against the potential of underage usage if the product remains on the market

The aging starts quite early with smoking and sun exposure. The combination of sunlight and a chemical environment caused by smoking and vaping can restrict blood flow to the skin over time which is needed to repair and regeneate healthy skin cells