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Tobacco, and other ingredients in tobacco products, can potentially cause allergies or allergy-like symptoms

95% CI 1.021.19 for low quality), and for cross-sectional studies (RR = 1.09

This finding suggests a protective mechanism against oxidative stress from smoke that may reflect the increase in GSH seen in long-term cigarette smokers

The study also showed that although the heritability of lung function and COPD was estimated to be between 38 and 50%, individual genetic variants only account for a small fraction of the overall risk associated with COPD [50]

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