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Towards solving the reproducibility crisis in surface-enhanced Raman spectroscopy-based pesticide detection

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Kumar R, Ferrie RP, Balmert LC, Kienzl M, Rifas-Shiman SL, Gold DR, Sordillo JE, Kleinman K, Camargo CA Jr, Litonjua AA, Oken E, Cook-Mills JM

In a study including N=58 patients affected by endometriosis and surgically diagnosed with the condition, the use of pycnogenol at 60mg/day for 48 weeks significantly reduced the symptoms score (N=26) as well as CA-125 levels (a serum marker of endometriosis) although in patients treated with hormones therapy (N=26), the benefits are even more pronounced

There is financial incentive and inducement to overpromise before all the research is in. Elysium, co-founded in 2014 by a prominent MIT scientist to commercialize the molecule nicotinamide riboside, a type of NAD booster, highlights its exclusive licensing agreement with Harvard and the Mayo Clinic and Sinclairs role as an inventor