Sources Phase 2 trial (NEJM) NEJM TRIUMPH-4 results Eli Lilly Related reading Retatrutide Dosage & Dosing Guide: Titration, Missed Doses, Taper Phase 3 titration schedule (246912 mg), missed-dose protocol, taper guidance, and dose-by-dose weight loss data
Pros: Higher bioavailability
Safety data from trials In a paper summarizing 6 randomized, double-blind, placebo-controlled human trials, AOD 9604 did not significantly affect IGF-1 levels, did not impair glucose tolerance, and no serious adverse events (SAEs) were attributed to AOD 9604
This leads to angiogenesisthe formation of new blood vessels
It enhances blood flow and angiogenesis, which supports the healing of larger muscle groups and soft tissues