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8 Furthermore, in myeloid leukaemia patients, GSH levels and its associated enzyme GSH transferase are commonly high, and are associated with increased risk of disease relapse and resistance to chemotherapy treatments

No published human trials

For example, in a randomized, double-blind, placebo-controlled trial in 60 participants diagnosed with an acute MI, neither mortality nor echocardiographic measures of cardiac function differed between patients treated with intravenous L-carnitine (6 g/day) for seven days followed by oral L-carnitine (3 g/day) for three months and those given a placebo (49)

In the tissue samples from mice, it was observed that treatment with ML364 notably mitigated the degree of fibrosis, as evidenced by the results of Massons trichrome and Sirius red staining (Fig