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If you find the injection site painful despite trying different areas, and this cannot be managed by a cold compress and over-the-counter pain medication, speak to your doctor straight away

If the blood-testis barrier becomes compromised through events (eg, surgery or infection) or due to vascular abnormalities (eg, varicocele), the development of antisperm antibodies, which target sperm and decrease their motility, can occur

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That matters because blood-sugar control does the opposite: HbA1c is nearly maxed out by 10 mg, so the top dose is justified by weight, not by additional glucose lowering. Body size also shifts the felt dose

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