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TB-500 works through Thymosin Beta-4's actin-sequestering domain to regulate cytoskeletal remodelling and promote endothelial migration, with particular documented activity in cardiac tissue

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Vitamin B12 is naturally synthesized by bacteria and found mainly in animal products, being essential for protection against anemia and for maintaining body energy

Therefore, drug-loaded MNPs are promising for the treatment of CNS diseases when crossing the BBB through the action of an external magnetic field

PubMed Central, doi:10.1038/sj.bjc.6604820