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Pathogen proliferation drives the secretion of a toxin cocktail (-toxin, perfringolysin O, and 2-toxin) that disrupts the abomasal mucosal barrier, which triggers necrosis, hemorrhage, and intramural gas accumulation and ultimately leads to severe structural degradation of the abomasal wall 70,71

They are designed to support specific systems such as blood flow, neural signaling, energy metabolism, or antioxidant defense rather than replace or suppress hormones

Effects of aging on articular cartilage homeostasis

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