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A further strength is the use of established methods that conform to proposals and regulatory stipulations on how AL should be assessed ( Synthesis of evidence for abuse liability determination for Velo ONPs Study 1 This study evaluated elements of AL for Velo Pouch products across three nicotine levels (4 mg, 8 mg, and 12 mg nicotine) in comparison to UB cigarette (a high-AL comparator) and NRT gum (a low-AL comparator) in current smokers and smokers who also use STPs

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[4] Kevin Schroth et al., Cigarette Trafficking in New York City: Now and Then Tobacco Control , August 26, 2025, [5] Kevin Schroth, et al., Cigarette Trafficking in New York City: Now and Then Tobacco Control , August 26, 2025, 1, [6] Shannon M