(Source 1) Suboptimal and deficient glutathione levels are associated with aging and an increased risk for chronic diseases, including: Mitochondrial dysfunction Neurodegenerative disease, including Alzheimers and Parkinsons disease Cancer Chronic liver disease Metabolic disease, including diabetes and hypertension Cardiovascular disease Pulmonary Infertility Autoimmune diseases, including lupus and multiple sclerosis Mental health disorders Cystic fibrosis (Source 1, 2) A viral illness, including SARS-CoV-2, the virus that causes Covid-19, can also cause glutathione deficiency
Hosseini, A., Koushesh Saba, M
Glutathione reduces the production of melanin, the pigment responsible for dark spots and uneven skin tone, while Vitamin C works to fade existing dark spots
Collagen improves skin firmness, hydration, and elasticity
Notably, the mechanisms of probiotics may involve modulation of gut microbiota composition, while prebiotics such as inulin-type fructans (ITF) can selectively promote the growth of beneficial bacteria like Bifidobacterium and Lactobacillus, enhancing SCFA production and subsequently improving gut barrier function, insulin sensitivity, and metabolic parameters (99, 110)