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Studies using clinical-stage ATX inhibitor IOA-289 in pancreatic cancer models revealed ATXs complex TME role: IOA-289 reduces connective tissue growth factor secretion in cancer-associated fibroblasts by regulating LPA/LPAR signaling

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Delivered intranasally for rapid absorption and high bioavailability, this innovative therapy targets key neurochemical pathways, providing benefits such as mental clarity, emotional stability, and neuroprotection

5-Amino-1MQ has not been approved by the FDA or any regulatory agency for human use