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doi: 10.1016/j.amsu.2021.102917

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Although GSSG represents approximately 1% of the total glutathione in the cell under basal conditions, a striking increase is found in cells undergoing oxidative stress

Present in reduced (unoxidized form)

Eosinophils, neutrophils, and monocytes contain peroxidases that catalyze the interaction between H 2 O 2 and halides leading to the formation of hypohalides, such as HOCl