This limitation makes polydopamine coatings especially appealing because they effectively penetrate mucus layers and improve uptake by epithelial cells an advantage not inherent to all zwitterionic systems
2016;17:3018 Bentham Science Publishers Ltd
Imidazole ketone Erastin (IKE) achieves markedly greater potency and stability through an imidazole ketone scaffold that enables durable target engagement while resisting metabolic clearance (76)
Think of it like choosing between a spa day and an emergency room visit
Haslbeck KM, Neundorfer B, Schlotzer-Schrehardtt U, Bierhaus A, Schleicher E, Pauli E, Haslbeck M, Hecht M, Nawroth P, Heuss D: Activation of the RAGE pathway: a general mechanism in the pathogenesis of polyneuropathies