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Glutathione isa substance made from the amino acids glycine, cysteine, and glutamic acid

According to research by Hou et al., cardamonin may enhance the chemosensitivity of the BGC823/5-Fu cell line to 5-Fu by suppressing the expression of Wnt target genes (-catenin, TCF5) and interfering with the -catenin/TCF4 complex formation

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However, vitamin C also supports healthy muscles, bones, and blood vessels

Yet, more recently, a metabolomic analysis reveals the importance of glutamine uptake by ASCT2 and its conversion into ROS-producing intermediate metabolite -Ketoglutarate as marker of sensitivity during sulfasalazine xCT-inhibition cell death in head and neck squamous cells carcinoma (46)