Reported effects are mild and transient: Localized irritation or redness at injection site, Mild fatigue or transient headache during initial days, Rare gastrointestinal upset (nausea, stomach discomfort)
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Some studies suggest that people with obesity may be more likely to have a vitamin B12 deficiency
Some common signs and symptoms include: Decreased cognitive function, such as issues with memory or understanding Fatigue Lethargy Constipation Feeling faint Depression or irritability Headache Difficulty maintaining balance Sore, swollen tongue, which may be pale yellow or very red Heart palpitations Mouth ulcers Par anesthesia (pins and needles) Vision changes B-12 deficiency risk factors Both diabetes and some medications for type 2 diabetes can increase the risk of vitamin B-12 deficiency
Also, another randomized double-blind study compared the efficacy of 100 mg diclofenac sodium soft gel (with or without 100 mg caffeine) with placebo during migraine attacks