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No significant adverse effects have been reported from animal studies or first-hand human experiences

While ubiquinone is a co-enzyme required for the function of oxidative phosphorylation, it is not considered a vitamin as it is synthesized from other amino acids

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366 Exogenous supplementation with spermidine can effectively promote the translation of TFEB, a transcription factor involved in autophagosome and lysosome biogenesis, through hypusinated EIF5A