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This might include a mix of treatments such as prescription medications to calm inflammation, joint-supporting supplements like glucosamine, physical therapy, and weight management

This is achieved through angiogenesis , which is the formation of new blood vessels

doi: 10.3389/fendo.2019.00027

Contraindications across the group commonly include pregnancy or breastfeeding and being under 18, with additional considerations such as active or recent cancer (CJC + Ipamorelin, IGF-1 LR3), active malignancy (Sermorelin), uncontrolled blood sugar disorders (CJC + Ipamorelin), uncontrolled metabolic or endocrine disorders (IGF-1 LR3, MOTS-C), severe liver or kidney disease (MOTS-C), autoimmune disorders requiring careful metabolic regulation (MOTS-C), and use of insulin or oral hypoglycaemic medications due to hypoglycaemia risk (MOTS-C)

Rome: FAO (2015)