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Given that acetyl-CoA also serves as the precursor for PUFA synthesis, its excessive accumulation provides the substrate foundation for lipid peroxidation, thereby fostering a pro-ferroptotic microenvironment

There isn't a massive, decades-old body of literature to fall back on

doi: 10.1016/S0021-9258(17)33581-0 52 WrigleyNGHeatherJVBonsignoreADe FloraA

The exact number of sessions depends on treatment goals, dosage protocols, and individual response, with maintenance sessions often recommended for long-term results