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Deficiency is particularly common in elderly people because the ability to absorb vitamin B12 can decrease with age

doi: 10.1038/s41467-022-31218-2

higher injection frequency is more effective than higher individual doses Topical application is not relevant for GI conditions Note: GHK-Cu is not typically taken orally as the copper complex may not survive GI transit in its intact bioactive form Limitations: GHK-Cu's strongest human clinical evidence is topical and dermatological