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Conversely, short-chain fatty acids (SCFAs) produced by fiber-fermenting bacteria foster regulatory T cells (Tregs) that secrete anti-inflammatory cytokines like IL-10 [40]

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In particular, these dietary patterns can inhibit Th17 cell differentiation, increase Treg cell proliferation, and significantly lower the expression levels of pro-inflammatory eicosanoid biosynthesis enzymes (like COX1, COX2, and ALOX5), all of which can mitigate inflammatory responses in MS patients and enhance their quality of life (284286)

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