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He made substantial contributions to the concept of the study and followed up the work to ensure that it was original and complied with the research ethics and guidelines of this journal
The FDA added it to injectable semaglutide in January 2025, and it climbs the dose axis like everything else. Burning or tingling skin tracks the dose, not the weight lost, and an active-comparator study put the risk about twice that of another weight-loss drug. The mechanism is unsettled: the tempting "it is the drugs signaling arm" story is ruled out, because the strongest GLP-1 signaler in the class carries no such signal
For healing a torn tendon or a strained muscle, you need the compound to actually reach the tissue, and injection is the only route with consistent evidence for that
If the question were only do they help injured tissue heal in animals, the answer would look similar for the two
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