Kuramochi cells, which are sensitive to DNA-damaging agents but modestly HR proficient 27 , also showed increased RAD51 foci following treatment with DNA-damaging agents combined with KG or carnitine supplementation (Extended Data Fig
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- when there is risk of torsades de pointes, for example in patients with prolonged QT, concomitant administration of other medications that produce torsades de pointes (amiodarone, quinidine, bepridil, IV erythromycin, halofrantine, pentamidine, sparfloxacin, sultopride, vincamine, betrilio, disopyramide, sotalol, etc)
The left cells were gently mixed with the prepared GSH magnetic beads suspension and incubated on a rotator at 10 rpm for 15 min at room temperature
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