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Understanding the mechanisms underlying METH-induced neurotoxicity is essential for developing effective treatment strategies to mitigate its devastating effects

The ins and outs of RND efflux pumps in Escherichia coli

It is proposed that the C* domain located at the C-terminus of CesAand the TE domain located at the C-terminus of CesB works as a cooperative esterification and depsipeptide elongation center, repeatedly recruiting the action of the C* domain to oligomerize tetradepsipeptides to give octa- and dodecadepsipeptides prior to macrocyclization by the TE domain

Glutathioneplays a powerful role in detoxifying and removing carcinogens