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Research reveals that senescent cells show upregulation of pro-apoptotic initiators PUMA and BIM while anti-apoptotic guardian BCL-2 is reduced, suggesting these cells are ready to undergo apoptosis but the execution is restrained by the FOXO4-p53 interaction

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According to the policy of the Animal Experimentation Ethics Committee of China Pharmaceutical University, such minimal-risk procedures are exempt from ethical approval

By influencing this pathway, it is being researched for its potential to: Support metabolic efficiency Influence fat storage mechanisms Promote a more favorable energy balance While research is ongoing, interest in this compound continues to grow within the fitness and wellness communities