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Researchers planning new work should review the most current literature before designing protocols, with attention to the gap between preclinical breadth and clinical-trial depth

One promising strategy is to attach chemotherapeutic drugs to molecular chaperones (antibodies) that specifically target cancer cells

256 Increased cystine uptake and elevated extracellular glutamate levels can enhance hypoxic neuronal injury in cortical cultures from mice

Lake RA, van der Most RG

in vitro and in vivo tests have been performed to demonstrate the importance of RBC antioxidant enzymes in protecting target cells from reactive oxygen species (ROS) (4, 5)