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FOXO4 should be capable of continuing to play a vital role in the transcription of genes for antioxidant enzymes, such as manganese superoxide dismutase (MnSOD), catalase (CAT), and glutathione peroxidase (GPX)

Yes they're commonly stacked

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Here, both Mtnr1a and Mtnr1b as well as Aanat and Asmt were again undetected, suggesting that ILC2s did indeed not express the genes for canonical melatonin receptors or those genes required for the synthesis of melatonin ( Supplementary Figure 3E )