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Serious complications are uncommon but should be reported promptly to a clinician

Hypoxia or genetic alterations leading to stabilization of HIF induce tumor angiogenesis Hyper-proliferation of tumor cells results in increased oxygen consumption, and when the tumor mass surpass the blood supply the tumor becomes hypoxic

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Association of altered serum micrornas with perihematomal edema after acute intracerebral hemorrhage

Companies with these practices face lower regulatory risk