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The researchers proposed that the senolytic effect observed in these cells is attributable not only to the disruption of the PI3K/AKT pathway but also to interference with the ERK/MEP pathway, which plays a crucial role in regulating inflammation and resistance to apoptosis [123]

Importantly, diabetic and non-diabetic PD subjects show significant differences in SN and striatum denervation or cortical cholinergic denervation, as assessed by PET imaging

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They study how this blend may affect cellular energy balance and lipid metabolism pathways

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