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Acting as an MC4R agonist, it has been shown to promote satiety, reduce caloric intake, and support weight loss

It binds to multiple melanocortin receptor subtypes, but its primary effects come through two: MC1R (Melanocortin-1 Receptor) expressed on melanocytes in the skin

Emerging literary data have revealed a dynamic bidirectional interaction between gut microbiota and the nervous system, described by the microbiotagutbrain axis

In very rare cases, some individuals may experience digestive discomfort with oral supplements

It is not possible to determine how many patients would be needed to power such a study for comparisons between the three separate groups