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A significant knowledge gap exists in the heterogeneity of collagen crosslinking and associated mechanisms (including types of crosslinks, LOX, LH, etc .), particularly within critical transition regions of the enthesis

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Tissue injury and hypoxia promote malignant progression of prostate cancer by inducing CXCL13 expression in tumor myofibroblasts

The major treatment for blood abnormalities in sickle cell anemia is targeted at increasing the amounts of fetal hemoglobin, a molecule that functions similarly to hemoglobin but lacks the sickle cell mutation and is primarily found in the developing fetus