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Typical causes include hormonal changes and sun damage

Renal biopsy specimens from DKD patients reveal elevated expression of ferroptosis-associated proteinssuch as acyl-CoA synthetase long-chain family member 4 (ACSL4) and prostaglandin-endoperoxide synthase 2accompanied by marked downregulation of glutathione peroxidase 4 (GPX4), a key suppressor of ferroptosis (127)

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They synthesized inorganic tellurium nanowires (TeNWs), which produce toxic TeO 6 6- under intracellular overexpressed H 2 O 2 condition and boost enhanced ROS generation in the tumor site