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Effect of vitamins on skeletal health Heat stress induces oxidative stress that directly compromises the gut barrier function, leading to a massive reduction in the absorption of bone minerals like calcium and phosphorus (174)

119 In addition, other signalling pathways, such as the noncanonical Wnt, JAK/STAT, and Hedgehog (Hh) pathways, exhibit signalling crosstalk with the Wnt/-catenin signalling pathway, jointly achieving the regulation of bone homeostasis

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GPX4 released from ferroptotic cancer cells functions as a DAMP that suppresses antitumor immunity by engaging the zona pellucida glycoprotein 3 (ZP3) receptor on dendritic cells 101

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