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We first infused late gestation fetal sheep ( n = 10) with either IGF-1 LR3 (IGF-1) or vehicle control (CON) and measured basal insulin secretion and in vivo GSIS utilizing a hyperglycemic clamp

As a master antioxidant, glutathione helps: Neutralise free radicals Reduce inflammatory responses Protect skin cells from UV-induced damage This helps prevent the reactivation of pigmentation at its root cause

We detected a lower arginine/proline media ratio (lower metabolite concentrations in arginine medium compared to proline medium) for 2-oxoglutarate, linoleate, 11,14-eicosadienote, proline, 2-aminoadipate, pyroglutamate, para-toluate, 2-aminobutyrate, lysine, glutamine, alanine, glutamate, serine, and margarate in gdh3 / gdh3 mutants compared to wild-type

PLoS One 8 , e82459, (2013)

Nat Commun 12(1):5045, 2021