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Erythrocytes are enucleated cells with a cytoplasm without organelles and rich in hemoglobin (Hb), which represents about 95% of total erythrocytes cytoplasmic proteins [4, 5]

Several studies analyzed the exo-metabolome in culture media to examine hepatotoxic effects of xenobiotics ( The analysis of the exometabolome is a valuable tool for evaluating drug-induced liver damage, particularly in cases where obtaining a liver sample from DILI patients is not feasible for medical and ethical reasons

[PubMed] Hiltz ME, Catania A, Lipton JM

[1] [4] History [edit] Graves' disease owes its name to the Anglo-Irish doctor Robert James Graves, [44] who described a case of goiter with exophthalmos in 1835

His formula was groundbreaking in its simplicity and effectiveness