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Bioinformatics analysis We used the GEPIA2 database to analyze the expression levels of MFAP2 in colon adenocarcinoma (COAD) samples, which included 349 healthy volunteers and 275 CRC patients

Notably, a meta-analysis of the effects of CLA on inflammatory factors in adults indicates that CLA reduces levels of pro-inflammatory cytokines (e.g., TNF- and IL-6), while slightly increasing C-reactive protein (CRP) levels (99)

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To increase the effective concentration of antioxidants, some trials used high doses of antioxidants, which in turn promote oxidation