Iron also serves as a cofactor for tyrosine hydroxylase, the rate-limiting enzyme in dopamine synthesis, and for the dopamine D2 receptor, playing a crucial role in myelin synthesis for dopamine production in the brain [72]
5 Conclusion The antioxidant effects of Spirulina platensis aqueous extract (SPAE) contributed to regulating biochemical parameters, including liver enzymes and lipid profiles, in male rats subjected to dexamethasone-induced oxidative stress
Hypoxia-inducible factors (HIFs) orchestrate adaptive transcriptional programs that enhance glycolysis, angiogenesis, acidosis, and survival signaling, while metabolic rewiring toward aerobic glycolysis, glutaminolysis, and lipid metabolism supports rapid proliferation and therapeutic resistance
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