Oxidative modifications to cellular components in plants
Furthermore, GEN are reported to induce liver cancer MHCC97-L cells apoptosis and activity of caspase-3 and caspase-9 through inhibiting JNK pathway (Liu et al., 2019)
The simulated profiles for the reduced and comproportionation models, as well as the parameter values generated from the fitting process, are located in the supplementary information
Additional information DISCLOSURE/CONFLICT OF INTEREST Michael Berk declares that over the past three years, he has received compensation from Stanley Medical Research Foundation, MBF, NHMRC, Beyond Blue, Geelong Medical Research Foundation, Bristol Myers Squibb, Eli Lilly, Glaxo SmithKline, Organon, Norvatis, Mayne Pharma and Servier
The AlphaFold prediction also showed that the three-dimensional structure of SsCm1 is obviously different from the Cms with enzyme function, suggesting that the structural variation caused by the differentiation of key amino acids in enzyme activity may be the reason why SsCm1 loses its enzyme function