Biochemistry 40:1413442, PMID: 11714266 Reynaert NL, van der Vliet A, Guala AS, McGovern T, Hristova M, Pantano C, Heintz NH, Heim J, Ho YS, Matthews DE, Wouters EF, JanssenHeininger YM (2006) Dynamic redox control of NF-kappaB through glutaredoxin-regulated S -glutathionylation of inhibitory kappaB kinase beta
Metformin , commonly prescribed for type 2 diabetes, can reduce B12 absorption with long-term use
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However, while these caspases were found to be functionally active in in vitro experiments, they were not activated by a variety of proapoptotic stimuli, indicating a unique regulation of apoptosis in RBCs