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MZB differentiation is blocked in Gclc -deficient mice The loss of MZB in Gclc fl/fl Mb1-Cre + mice prompted us to investigate the possibility of defects in the trafficking of MZB in the spleen

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In December, the companys shares rocketed 209% when it announced that the candidate had hit both primary endpoints and a secondary endpoint in the Phase III MAESTRO-NASH biopsy trial