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The mechanism involves attraction of immune cells and mesenchymal stem cells to wound sites, along with stimulation of glycosaminoglycan production and decorin synthesis, both of which are critical for proper extracellular matrix assembly

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The mechanisms by which GSHee augments fentanyl-induced analgesia are probably multi-factorial and likely to involve modulation of analgesia-signaling pathways within the periphery, spinal cord and brain 15