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Severe Anemia Risks: In people with severe megaloblastic anemia, aggressive treatment can cause low potassium (hypokalemia) and sudden, serious complications

Research Highlights No peer-reviewed studies published as of June 2025

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Decision-making with endpoints and backup plans improves safety

Last reviewed: June 16, 2026 Last updated: June 16, 2026 Written by: Jay Hastings, CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations