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Toward optimizing the use of deferasirox: potential benefits of combined use with deferoxamine

A comprehensive B-complex supplement fills gaps left by reduced food intake

In contrast, ALOX12 is required for ferroptosis caused by TP53-mediated downregulation of SLC7A11 (Chu et al., 2019)

7.6.1 Strategic research priorities Future research should prioritize expanding multi-omics approaches for comprehensive exposure assessment, investigating cumulative and mixture effects to refine risk predictions, validating transgenerational epigenetic inheritance in human cohorts, developing targeted interventions for mitigating EED-induced reproductive damage, and establishing international regulatory standards for exposure limits and safety assessment