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However, binding and enzyme inhibition studies revealed a 100-fold more potent affinity for GSTO1 than PDI

Glutathione is involved in quenching reactive oxygen (Foyer et al., 1994) and nitrogen (Airak et al., 2011) species

Oxidative stress and endometriosis: a systematic review of the literature

Researchers believe this is due to increased ROS (increased oxidative stress) in the pancreatic beta cells.[ref] Related article : Type 2 Diabetes Genes Fatty liver disease: High homocysteine levels are associated with NAFLD (fatty liver disease, MAFLD)