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The enrichment of S-palmitoylation sites at the C-terminal region of ATG2A suggests that S-palmitoylation may facilitate the anchoring of the C-terminus to the ER membrane

The brain utilizes a large portion of the total pool of body glucose for its metabolic requirements, both in the synthesis of ATP and also as substrate for the formation of various neurotransmitters, including acetylcholine

Mechanistically, GSTM2 interacted with ASK1 and suppressed its phosphorylation and the activation of subsequent downstream p38-JNK signalling

[Abstract]2026 May 30;14(6):1231

Members of the monomeric G-protein Rab family, specifically Rab8a, Rab13, and TBC1 domain family member 4 (encoded by the TBC1D4 gene) have been shown to be critical to the insulin-stimulated mobilization of GLUT4 to the plasma membrane in skeletal muscle while Rab10 is involved in the process in adipocytes