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Studies have characterised MC1R-mediated anti-inflammatory signalling in macrophage and neutrophil models , examining cAMP-mediated NF-B suppression and cytokine production inhibition and and have examined MT-1s effects in inflammatory bowel disease, arthritis, and ischaemia-reperfusion injury models where melanocortin anti-inflammatory biology has been characterised

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Additionally, some patients may be encouraged to take peptides that contain proteins with anti-inflammatory properties

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