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Besides, toxicity screening performed on several types of metal oxide NPs observed that CuO and ZnO NPs induced the highest toxicity in acute models both in vitro and in vivo , mainly due to significant promotion of pro-inflammatory cytokines release and inhibition of macrophage viability (Vandebriel et al., 2018)

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Natl Cancer Inst 103, 817825 (2011)

mean CD4 cell count was 606 cells/mm

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