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In neuronal cells, IGF1 protects against prion diseases caused by mitochondrial dysfunction and increased ROS production via inhibition of Bax translocation (Park et al., 2012)
Monitoring during a peptide cycle is straightforward: track subjective changes (sleep, energy, skin texture), use consistent photographs to document visible changes, and consider follow-up lab work at the end of a cycle to assess whether biomarkers have moved in the expected direction
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