If significant deficiency is confirmed via blood test, a loading dose protocol may be recommended in line with NICE guidance typically more frequent injections over the initial weeks to rapidly restore levels
Manipulating this pathway may lead to many dividends
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Patients come in with persistent pain, but standard optionsNSAIDs, corticosteroids, biologics, and eventually surgerydo little more than suppress symptoms or delay progression
Pituitary (2009) 12(4):3304