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Absolute reductions in current smoking prevalence from 2011/12 to 2019/20 were between 7.9% and 9% in 15-24, 25-34 and 35-44 year olds (relative reductions 29-42%), but were only between 0% and 2% (relative reductions 0-20%) in the 45 years and over age groups (figure 2)

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Both apoptosis and programmed necrosis pathways were upregulated

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