Here, we briefly review three groups of models: cellular ( in vitro and ex vivo ), rodent ( in vivo ), and non-human primates ( in vivo , ex vivo ) and how much each model helps in advancing our understanding of Meth effects
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Individual 1 mM lipid stocks of PE-18:0/18:1, PE-18:0/20:4, PE-P-18:0/20:4 and PC-18:0/20:4 were prepared in chloroform
cerevisiae KACC 48331 cells cultured at 30 C and 250 rpm for 48 h in 5 mL of YP20D medium were exposed to UV radiation to obtain ~2% survival rates
The use of a methyl group is optimum in that it is small enough to not influence the overall activity of the molecule, while the rationale behind the location of the modification is to protect the most common degradation location of the peptides, i.e., the peptide bond